Sunday, September 27, 2009

Findings from University College broaden understanding of diabetes. USA, LLC

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Investigators publish new data in the report 'Dietary patterns and 15-y risks of major coronary events, diabetes, and mortality.' "Few studies have examined the long-term effect of habitual diet on risks of incident diabetes, coronary heart disease, and mortality. We analyzed the prospective relation of dietary patterns with incident chronic disease and mortality during 15 y of follow-up in the Whitehall II study," investigators in London, the United Kingdom report (see also Diabetes).

"We conducted a prospective analysis (106,633 person-years at risk) among men and women (n=7731) with a mean age of 50 y at the time of dietary assessment (127-item food-frequency questionnaire). Coronary death or nonfatal myocardial infarction and incident diabetes were verified by record tracing and oral-glucose-tolerance tests. Cluster analysis identified 4 dietary patterns at baseline. The patterns were termed unhealthy (white bread, processed meat, fries, and full-cream milk; n=2665), sweet (white bread, biscuits, cakes, processed meat, and high-fat dairy products; n=1042), Mediterranean-like (fruit, vegetables, rice, pasta, and wine; n=1361), and healthy (fruit, vegetables, whole-meal bread, low-fat dairy, and little alcohol; n=2663). Compared with the unhealthy pattern, the healthy pattern reduced the risk of coronary death or nonfatal myocardial infarction and diabetes; hazard ratios (95% CI) were 0.71 (0.51, 0.98) and 0.74 (0.58, 0.94), respectively, after adjustment for age, sex, ethnicity, dietary energy misreporting, social position, smoking status, and leisure-time physical activity. Dietary pattern was not associated with all-cause mortality. Residual confounding by socioeconomic factors was unlikely to account for the observed dietary effects. The healthy eating pattern reduced risks of diabetes and major coronary events," wrote E.J. Brunner and colleagues, University College.

The researchers concluded: "Such dietary patterns offer considerable health benefits to individuals and contribute to public health."

Brunner and colleagues published their study in The American Journal of Clinical Nutrition (Dietary patterns and 15-y risks of major coronary events, diabetes, and mortality. The American Journal of Clinical Nutrition, 2008;87(5):1414-21).

For additional information, contact E.J. Brunner, University College London, Dept. of Epidemiology and Public Health, London, UK.

The publisher of the The American Journal of Clinical Nutrition can be contacted at: American Society Clinical Nutrition, 9650 Rockville Pike, Subscriptions, RM L-3300, Bethesda, MD 20814-3998, USA.

Keywords: United Kingdom, London, Alternative Medicine, Cardiology, Chronic Disease, Coronary Heart Disease, Diabetes, Heart Attack, Heart Disease, Myocardial Infarction, Therapy, Treatment.

This article was prepared by Health & Medicine Week editors from staff and other reports. Copyright 2008, Health & Medicine Week via

Source Citation:"Findings from University College broaden understanding of diabetes." Health & Medicine Week (May 26, 2008): 3466. Academic OneFile. Gale. BROWARD COUNTY LIBRARY. 27 Sept. 2009

Gale Document Number:A181037936

Disclaimer:This information is not a tool for self-diagnosis or a substitute for professional

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